Coronavirus update from David Baker. Thank you all for your contributions!
https://boinc.bakerlab.org/rosetta/forum_thread.php?id=14226Here is a short video of David Baker describing some exciting results from de novo designs targeting SARS-Cov-2.
Thank you all for your contributions to this research! Although R@h was not directly used for the work described in the publication (link provided below), R@h was used for designing relevant scaffolds. Additionally, there are currently many similar designs that bind SARS-Cov-2 and related targets that were engineered using R@h.
https://www.youtube.com/embed/ODEIN5V3yLg
More information is available from the publication, De novo design of picomolar SARS-CoV-2 mini protein inhibitors .
大意:项目方设计了一个新冠病毒的小蛋白抑制剂,抑制剂设计本身没有使用R@h,但是R@h设计了相关的脚手架蛋白。具体可以看楼上发的论文链接。非相关专业,翻译错误请轻喷
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