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本帖最后由 金鹏 于 2014-4-11 13:18 编辑
推荐V7.44加beta参数是必需的 A+N通吃
N卡终于有CORE17口粮了
New GPU Project 9101
Unread postby msultan » Thu Apr 10, 2014 7:54 am
Hello all,
I am releasing a new beta GPU project 9101 on the fyn kinase.The fyn kinase is an enzyme present in multiple signaling pathways whose aberrant behavior leads to cancerous cell growth, and has also been implicated in the invasion of the dengue virus. This project continues the Pande Lab's effort to map out the conformational landscape of the src kinase family. Recent work from our lab on a similar kinase found a potentially druggable intermediate state(Shukla et al, Nature2014). The main aim of the present simulation is to get a better understanding of Fyn's dynamics in order to design better therapeutics.
More Science:
The link between fyn and dengue: http://www.ncbi.nlm.nih.gov/pubmed/23616652
Recent Src Results: http://www.nature.com/ncomms/2014/140303/ncomms4397/full/ncomms4397.html
Some Project Stats:
client-type beta
timeout 8.0
deadline 10.0
k-factor 0.75
gens 2000
min-core-version 46
natoms ~33000
stats-credit 4000
contact msultan <at> stanford.edu
my back of the envelope calculations show that it should give approximately 200k PPD based off information from internal testers. Message me either here or via email if the project is giving problems/issues with stats etc. Thanks for all your help!
Happy Folding!
Cheers,
Muneeb :D New GPU Project 9406
Unread postby cxh » Thu Apr 10, 2014 7:38 am
Here are some of the project details.
clones 5
min-core-version 46
natoms 78000
runs 1040
stats-credit 10500
timeout 3.5
deadline 4.5
In the same vein as 9401, this is a simulation of a disordered p53 peptide while binding to another protein. In this case, however, the binding partner is S100B, which is a cell cycle regulator. We hope to study how mutations in p53 may disrupt binding and, in the process, onset cancer.
Happy folding!
New GPU project 9407 (kind of new)
Postby ChristianVirtual » Sat Apr 05, 2014 5:42 pm
Got one, before announcement 8-) on GTX 780/Linux; looks like the twin of 9401
Project: 9407 (Run 151, Clone 0, Gen 0)
After 5 frames:
9407 (R:151 C:0 G:0) Status running TPF 6:25 Runtime 10:42:44 Credit ~ 63,229 PPD ~ 141,765
Very similar to 9401 New GPU Project 9408
Unread postby cxh » Thu Apr 10, 2014 7:41 am
Here are the project details:
min-core-version 46
natoms 52940
runs 6220
stats-credit 13000
timeout 10.9
deadline 14.1
This is actually a clone of project 9401. Project 9401 was retired after a work server failure.
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发表于 2014-4-11 08:23:40
发表于 2014-4-11 10:01:05