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A recent paper in Nature Biotechnology describes how we have combined computational protein design with the high throughput DNA sequencing methods developed for sequencing the human genome to generate potent influenza virus inhibitors. These designed proteins block infection by the flu virus in cell culture experiments, and they are now going through the (quite lengthy) process of being developed as possible anti-flu drugs.
在《自然生物技术》最近发表的一篇文章描述了我们如何结合计算蛋白质设计与高通量DNA测序方法开发的人类基因组的测序产生强有力的流感病毒抑制剂。这些设计蛋白质块感染流感病毒在细胞培养实验,他们目前正在通过(相当冗长的)正在开发的过程尽可能的抗流感药物。 |
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