Our Project
The project of Heidelberg's iGEM Team 2014 is dedicated to the modification of existing proteins, for example by attaching new structures to their ends and thereby changing the properties of the workhorses. As previously mentioned proteins have certain a function due to their conformation. So normally we don't want to destroy their original function, but how can we know whether the function is the same after we have attached parts? We analyze the new protein's folding with the attached sequences because if we choose the correct sequence between protein and our added part, we can minimize their influence on each other. But we have to try many different sequences (several hundred) with many different proteins (several thousand) to find out about the behavior of the sequences we try to attach.
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