https://secure.worldcommunitygri ... q.do?shortName=hcmd 来源
WCG内的资料转载如下：
Decrypthon Molecular Docking vs. FightAIDS@Home
Since November 2005, World Community Grid has been running FightAIDS@Home (FAAH). This project has been investigating computational ways to design effective, inexpensive drugs that stop the HIV virus, and thus the onset of AIDS.
The Decrypthon and FAAH projects are alike in that they both use computer programs which simulate the docking of two compounds/molecules together to see how well they bind to each other. FAAH is searching through many compounds that bind to a certain portion of an enzyme (a protein) called HIV protease needed by the HIV virus to replicate. If a compound is found that strongly attaches to a certain part of the HIV protease, it prevents it from functioning and thus keep HIV from replicating.
The Decrypthon project is also docking molecules, but doing this among all of the proteins, genes (DNA), and potential drugs (ligands) that seem to play a role in neuromuscular diseases. This is being done to better understand what specific roles all of these proteins play in both normal and disease processes.
大致是说明这部份与FightAIDS 研究方法方向相同,但仍有部份是异于FightAIDS的
有机会遇到再Po图上来~~目前也没遇到过 :)
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Last edited by alexpon on 2007-1-20 at 01:56 ]
