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[新闻] Help in the fight against COVID-19!

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发表于 2020-4-3 17:01:35 | 显示全部楼层 |阅读模式
http://boinc.bakerlab.org/rosetta/

With the recent COVID-19 outbreak, R@h has been used to predict the structure of proteins important to the disease as well as to produce new, stable mini-proteins to be used as potential therapeutics and diagnostics, like the one displayed above which is bound to part of the COVID-19 spike protein.

To help our research, we are happy to announce a new application update, and thanks to the help from the Arm development community, including Rex St. John, Dmitry Moskalchuk, David Tischler, Lloyd Watts, and Sahaj Sarup, we are excited to also include the Linux-ARM platform. With this update we will continue to make protein binders to COVID-19 and related targets using the latest Rosetta source.

Thank you R@h volunteers for your continued support to this project. Your CPU hours are used not only to accurately model the structures of important proteins, but to design new ones as well. Let's band together and fight COVID-19!

More details will be available in the Discussion of this news post.

3 Apr 2020, 3:45:24 UTC · 讨论

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发表于 2020-4-3 19:52:50 | 显示全部楼层
安卓恢复发包了,而且得分率特别高,建议多用手机刷分
发送时间
结果上报时间
或者上报期限
解释
状态
运行时间
(秒)
CPU 时间
(秒)
积分
计算程序

3 Apr 2020, 8:20:54 UTC3 Apr 2020, 11:46:35 UTC已完成,通过验证
3,762.77
3,599.38
150.52
Rosetta for Portable Devices v4.12
arm-android-linux-gnu

3 Apr 2020, 8:20:54 UTC3 Apr 2020, 11:46:35 UTC已完成,通过验证
4,344.61
4,235.24
174.39
Rosetta for Portable Devices v4.12
arm-android-linux-gnu

3 Apr 2020, 8:12:45 UTC3 Apr 2020, 11:39:30 UTC已完成,通过验证
3,934.47
3,825.08
157.94
Rosetta for Portable Devices v4.12
arm-android-linux-gnu

3 Apr 2020, 8:12:45 UTC3 Apr 2020, 10:34:09 UTC已完成,通过验证
3,863.67
3,852.90
157.23
Rosetta for Portable Devices v4.12
arm-android-linux-gnu

3 Apr 2020, 8:12:45 UTC3 Apr 2020, 10:43:30 UTC已完成,通过验证
3,880.47
3,869.30
158.60
Rosetta for Portable Devices v4.12
arm-android-linux-gnu

3 Apr 2020, 7:51:09 UTC3 Apr 2020, 10:28:09 UTC已完成,通过验证
5,474.07
5,078.08
227.63
Rosetta for Portable Devices v4.12
arm-android-linux-gnu

3 Apr 2020, 7:12:02 UTC3 Apr 2020, 9:38:30 UTC已完成,通过验证
4,659.22
3,800.96
197.28
Rosetta for Portable Devices v4.12
arm-android-linux-gnu

3 Apr 2020, 7:06:39 UTC3 Apr 2020, 9:28:40 UTC已完成,通过验证
4,553.26
3,601.96
196.19
Rosetta for Portable Devices v4.12
arm-android-linux-gnu

3 Apr 2020, 6:48:29 UTC3 Apr 2020, 8:57:01 UTC已完成,通过验证
3,951.86
3,751.29
168.30
Rosetta for Portable Devices v4.12
arm-android-linux-gnu

3 Apr 2020, 5:53:54 UTC3 Apr 2020, 8:12:45 UTC已完成,通过验证
3,642.37
3,607.55
156.09
Rosetta for Portable Devices v4.12
arm-android-linux-gnu

3 Apr 2020, 5:52:38 UTC3 Apr 2020, 8:20:54 UTC已完成,通过验证
4,456.01
4,410.19
192.62
Rosetta for Portable Devices v4.12
arm-android-linux-gnu

3 Apr 2020, 5:37:59 UTC3 Apr 2020, 7:51:09 UTC已完成,通过验证
3,765.47
3,735.46
159.37
Rosetta for Portable Devices v4.12
arm-android-linux-gnu

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发表于 2020-4-4 01:39:19 | 显示全部楼层
顺便贴一下3月31日项目管理员透露的项目最新动态
1. As mentioned before we spiked ~4x or more in computing in the last week. So far our infrastructure has been handling this okay but we will definitely look into expansion and optimization as we expect many more volunteers to join in the near future. Also, our bandwidth has maxed out on a few occasions but has been okay since.

2. A number of outside groups have approached us to help.

a. The ARM developer community came together and helped port Rosetta for aarch64. The application is being tested on Ralph@home currently and will be released soon along with an announcement.
b. We are in communication with Microsoft to help us integrate and support Rosetta BOINC builds into the Rosetta Commons build and testing infrastructure and possibly with other developments.
c. We are in communication with Charity Engine to possibly use their infrastructure to run GPU machine learning based jobs and to help integrate such capability to R@h.

3. We have plenty of COVID-19 jobs but there may be a pause from time to time to give us a chance to prepare them based on previous results and new targets/methods etc.
4. We hope to update the Rosetta apps that are currently being tested on Ralph soon and plan to do another update in the near future, so 2 application updates are lined up for the near future.
5. With these updates, we hope to recruit more researchers within the lab to use this resource, but in the immediate future, priority will of course be towards COVID-19, specifically for the design of scaffolds and binders to COVID-19 targets as possible therapeutics.
项目总算力一周内提高了3倍多,任务包供不应求;好些个项目组已经与Rosetta接洽,提供下一步的优化与帮助,例如64位ARM任务包开发,未来可能推出的GPU机器学习任务包等等
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发表于 2020-4-6 16:14:03 | 显示全部楼层
https://boinc.bakerlab.org/rosetta/forum_thread.php?id=13702
參考囉 沒法指定包,PC是有載到
2020/4/6 下午 02:15:01 | Rosetta@home | Scheduler request completed: got 3 new tasks
2020/4/6 下午 02:15:03 | Rosetta@home | Started download of rosetta_4.12_windows_intelx86.exe
2020/4/6 下午 02:16:01 | Rosetta@home | Finished download of 8cx5cm5v_Mini_Protein_binds_IL1R_COVID-19_design2.zip
2020/4/6 下午 02:16:02 | Rosetta@home | Finished download of 8cx5cm5v_Mini_Protein_binds_IL1R_COVID-19_design2.flags
2020/4/6 下午 02:16:05 | Rosetta@home | Finished download of 1uq6kp3y_Mini_Protein_binds_IL1R_COVID-19_design2.zip
2020/4/6 下午 02:16:06 | Rosetta@home | Finished download of 1uq6kp3y_Mini_Protein_binds_IL1R_COVID-19_design2.flags
2020/4/6 下午 02:16:09 | Rosetta@home | Finished download of 3vs9ys6d_Mini_Protein_binds_IL1R_COVID-19_design2.zip
2020/4/6 下午 02:16:11 | Rosetta@home | Finished download of 3vs9ys6d_Mini_Protein_binds_IL1R_COVID-19_design2.flags
2020/4/6 下午 02:20:09 | Rosetta@home | Finished download of minirosetta_database_357d5d93529_n_methyl.zip
2020/4/6 下午 02:20:14 | Rosetta@home | Starting task 1uq6kp3y_Mini_Protein_binds_IL1R_COVID-19_design2_SAVE_ALL_OUT_905258_2_0
2020/4/6 下午 02:23:24 | Rosetta@home | Starting task 3vs9ys6d_Mini_Protein_binds_IL1R_COVID-19_design2_SAVE_ALL_OUT_905258_2_0
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