Influenza Antiviral Drug Search:常见问题解答

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Influenza Antiviral Drug Search 的常见问题解答







How soon is a new influenza drug going to be available?

In just several weeks, we will start identifying candidates for laboratory examination from the analysis on World Community Grid. It will then take anywhere from a few months to years to complete the entire process of distributing new drugs. During this time, when good candidates are found, they will proceed to laboratory testing phases. These ultimately lead to clinical trials and hopefully a drug available for use. The entire process can take years depending on the details and any problems encountered. Thus, we do not know how long it will really take nor when and if suitable candidates will be found.

However, we do know that the process of searching for drug candidates among the millions of potential compounds can be greatly accelerated using World Community Grid, compared to using conventional laboratory work or the limited resources typically available to the researchers.

What is the difference between influenza immunizations and antiviral drugs like Tamiflu and Relenza?

Influenza vaccine injections give your body immunity to the particular strains of influenza virus that the specific vaccine was manufactured to address. Once a person receives this vaccine, immunization for those strains typically lasts for many years. However, this immunization usually does not work for new strains. Because influenza mutates rapidly, new strains are formed all of the time. Influenza antiviral drugs are used to treat sever cases of the disease once a person has contracted an influenza strain for which he or she is not immune. Antiviral drugs such as oseltamivir (commercial name Tamiflu) and zanamivir (commercial name Relenza) help retard the spread of the virus in the body, once a patient has contracted influenza. However, these drugs are not effective against all types of influenza and in addition new drug-resistant strains are evolving. This is why this type of antiviral research is important. The antiviral drugs should only be used under the guidance of a doctor because other uses can encourage drug resistant strains of the virus to develop.

How do I keep from getting H1N1 influenza?

There is no guaranteed way to avoid getting influenza. However, the following CDC guidelines of everyday actions could help you stay healthy:

  • Cover your nose and mouth with a tissue when you cough or sneeze, and throw the tissue in the trash after you use it.
  • Wash your hands often with soap and water, especially after you cough or sneeze. Alcohol-based hands cleaners are also effective.
  • Avoid touching your eyes, nose or mouth. Germs spread that way.
  • Stay home if you get sick. CDC recommends that you stay home from work or school and limit contact with others to keep from infecting them.

I think I may have H1N1 influenza. What should I do?

We recommend that you check with your doctor and visit the following sites for advice:

  • World Health Organization - FLUNET
  • Centers for Disease Control and Prevention

What is the first picture on the Influenza Antiviral Drug Search detail page?

This is an image of the project's seal/icon and was designed by Tzintzuni Garcia and Robert Malmstrom. The background contains a stylized influenza virus particle with its characteristic spikes. The eight gray bars inside the particle represent eight segments of the influenza genome. The stylized virus particle is overlaid with the image of a compound signifying the search for an antiviral drug.