[BOINC] [生命科学类及其他] World Community Grid

vmzy

Mar 11, 2009 1:02:26 AM
250,000,000 Results!

We are extremely pleased to announce that World Community Grid volunteers have now returned more than 250 Million results. Results are what come out of each unit of work that you "crunch" on your computer and are sent to the researchers.

Our heartfelt thanks to the volunteer force -- the over 400,000 registered members who have downloaded World Community Grid on their computers. These computers have provided more than 223 thousand years of run time toward important research. We are extremely grateful for your contributions. Without you, this compute power would not be available for the very important research work we are helping to accelerate.

Thank you to the researchers for running their projects on World Community Grid. This includes:

1. The Institute for Systems Biology for the Human Proteome Folding - Phase 1 project;
2. The Scripps Research Institute for the FightAIDS@Home project;
3. The Cancer Institute of New Jersey, UMDNJ - Robert Wood Johnson Medical School for the Help Defeat Cancer project;
4. New York University for the Human Proteome Folding - Phase 2 project;
5. Fiocruz for the Genome Comparison project;
6. AFM, CNRS, INSERM, and Universite Pierre et Marie Curie for the Help Defeat Muscular Dystrophy - Phase 1 project;
7. University of Texas Medical Branch for the Discovering Dengue Drugs – Together project;
8. University of Cape Town for then AfricanClimate@Home project;
9. University Health Network and the Ontario Cancer Institute for the Help Conquer Cancer project;
10. University of Washington for the Nutritious Rice for the World project;
11. The Aspuru-Guzik group at Harvard University for The Clean Energy Project.

World Community Grid also thanks the more than 400 partners who are encouraging their employees, members, students and associates to participate on World Community Grid.

It continues to be our fondest hope that through the efforts of every World Community Grid participant, some human affliction will be eradicated in the near future.
大意：
返回结果总数达到2亿5千万。

vmzy

Mar 13, 2009 3:33:22 PM
Launch of the Help Fight Childhood Cancer Project

World Community Grid is pleased to launch the Help Fight Childhood Cancer project by the Chiba Cancer Center Research Institute and Chiba University in Chiba prefecture, Japan. The mission of the Help Fight Childhood Cancer project is to use World Community Grid to find drugs which can disable three particular proteins associated with neuroblastoma, one of the most frequently occurring solid tumors in children. Finding drugs to disable these proteins would potentially make the disease much more curable with chemotherapy. Neuroblastoma is one of the most common tumors in early childhood and often leads to death. If this project is successful, it could dramatically increase the cure rate for neuroblastoma. This project may provide the breakthrough for this disease that has eluded scientists thus far. For additional information on this project, please press the Research button in the upper navigation bar or click here.

Project Badge
If a member contributes a minimum of 14 days of CPU Run Time to this project, they will receive a Help Fight Childhood Cancer project badge on their member statistics page and next to their member name when they post in the forums. There is a different badge for each research project and beta testing. To read more about badges, click here.

Forums
In addition to providing information about this project, we have created a forum for discussions about the Help Fight Childhood Cancer project. To participate in this forum, please press the Forums button in the upper navigation bar or click here. Only forum authors with the title "Help Fight Childhood Cancer Scientist" are authorized to comment as representatives of the research organization: Chiba Cancer Center Research Institute (Chiba prefecture, Japan).

Project Participation
The Help Fight Childhood Cancer is the twelfth research project to be launched on World Community Grid and one of seven projects currently active. The other six active research projects are: Help Conquer Cancer (launched November, 2007), Discover Dengue Drugs – Together (launched August, 2007), Human Proteome Folding - Phase 2 (launched July, 2006), FightAIDS@Home Phase 2 (launched November, 2005), Nutritious Rice for the World (Launched May, 2008) and The Clean Energy Project (launched December, 2008). For more detailed information and FAQs about each of these projects, please click on the Research button in the upper navigation bar or click here. We thank all of our members for their valuable contributions to the projects to date and hope you will continue to help us process those, as well as this latest project.

Because there are seven research projects running on World Community Grid, your grid agent could receive work units from any of the projects depending on your Project profile. If you prefer, you may elect to focus your computer's time only on particular projects. To do so, press the My Grid button in the upper navigation bar and select My Projects or click here. Work is sent only to machines which meet minimum system requirements set for a particular project. To read more specifics on the system requirements for the Help Fight Childhood Cancer project and the other projects, click here.

Questions?
If you have any questions, World Community Grid provides you with four methods of obtaining assistance: (1) Review the FAQs found in the Help section of the website; (2) Review the forums to see if anyone has asked/answered the question that you have; (3) Ask the question in World Community Grid's Help Fight Childhood Cancer project forum found here and a Community Advisor or a more experienced member will provide an answer; or (4) Send an email to the support desk from the Contact Us link found at the bottom of every page of the website (except in the forums).

We thank you for contributing to the Help Fight Childhood Cancer project.
大意：
开始 Help Fight Childhood Cancer 项目。
由日本千叶大学主办。主要通过研究3种与神经细胞瘤（一种儿童多发性肿瘤）有关的蛋白质，希望能藉此提高该病的治愈率。

vmzy

May 5, 2009 2:42:09 PM

Launch of Influenza Antiviral Drug Search Project

World Community Grid is pleased to announce the launch of the Influenza Antiviral Drug Search project by Dr. Stan Watowich and his research team at The University of Texas Medical Branch (Galveston, Texas, USA). They are collaborating with researchers from the Galveston National Laboratory at UTMB (Galveston, Texas, USA) for testing of drug candidates. The mission of the Influenza Antiviral Drug Search project is to find new drugs that can stop the spread of an influenza infection in the body. The research will specifically address the influenza strains that have become drug resistant as well as new strains that are appearing. Identifying the chemical compounds that are the best candidates will accelerate the efforts to develop treatments that would be useful in managing seasonal influenza outbreaks, and future influenza epidemics and even pandemics. For more information click here. Project Badge If a member contributes a minimum of 14 days of CPU Run Time to this project, they will receive an Influenza Antiviral Drug Search project badge on their member statistics page and next to their member name when they post in the forums. There is a different badge for each research project and beta testing. To read more about badges, click here. Forums In addition to providing information about this project, we have created a forum for discussions about the Influenza Antiviral Drug Search project. To participate in this forum, please press the Forums button in the upper navigation bar or click here. Only forum authors with the title " Influenza Antiviral Drug Search and Discovering Dengue Drugs - Together Scientist" are authorized to comment as representatives of the research organization: The University of Texas Medical Branch (Galveston, Texas, USA). Project Participation Influenza Antiviral Drug Search is the thirteenth research project to be launched on World Community Grid and one of eight projects currently active. The other seven active research projects are: Help Conquer Cancer (launched November, 2007), Discover Dengue Drugs – Together (launched August, 2007), Human Proteome Folding - Phase 2 (launched July, 2006), FightAIDS@Home Phase 2 (launched November, 2005), Nutritious Rice for the World (Launched May, 2008), The Clean Energy Project (launched December, 2008) and Help Fight Childhood Cancer (launched March, 2009) . For more detailed information and FAQs about each of these projects, please click on the Research button in the upper navigation bar or click here. We thank all of our members for their valuable contributions to the projects to date and hope you will continue to help us process those, as well as this latest project. Because there are eight research projects running on World Community Grid, your grid software could receive workunits from any of the projects depending on your Project profile. If you prefer, you may elect to focus your computer's time only on particular projects. To do so, press the My Grid button in the upper navigation bar and select My Projects or click here. Work is sent only to machines which meet minimum system requirements set for a particular project. To read more specifics on the system requirements for the Influenza Antiviral Drug Search project and the other projects, click here. Questions? If you have any questions, World Community Grid provides you with four methods of obtaining assistance: (1) Review the FAQs found in the HELP section of the website; (2) Review the forums to see if anyone has asked/answered the question that you have; (3) Ask the question in World Community Grid's Influenza Antiviral Drug Search project forum found here and a Community Advisor or a more experienced member will provide an answer; or (4) Send an email to the support desk from the Contact Us link found at the bottom of every page of the website (except in the forums). We thank you for contributing to the Influenza Antiviral Drug Search project

大意：
开始流感疫苗研究项目。由德克萨斯州立大学主持。

zglloo

新项目 最近R@H 也关注H1N1   WCG也开始关注啦！

[ 本帖最后由 zglloo 于 2009-5-6 22:02 编辑 ]

vmzy

May 12, 2009 2:21:09 PM

Launch of the Help Cure Muscular Dystrophy – Phase 2 Project

World Community Grid is pleased to launch the Help Cure Muscular Dystrophy – Phase 2 project by researchers supported by Decrypthon, a partnership between AFM (French Muscular Dystrophy Association), CNRS (French National Center for Scientific Research) , and Unversite Pierre et Marie Curie. The mission of the Help Cure Muscular Dystrophy – Phase 2 project is to investigate protein-protein interactions for more than 2,200 proteins whose structures are known, with particular focus on those proteins that play a role in neuromuscular diseases. The database of information produced will help researchers design molecules to inhibit or enhance binding of particular macromolecules, hopefully leading to better treatments for muscular dystrophy and other neuromuscular diseases. For additional information on this project, please press the Research button in the upper navigation bar or click here. Project Badge If a member contributes a minimum of 14 days of CPU Run Time to this project, they will receive a Help Cure Muscular Dystrophy – Phase 2 project badge on their member statistics page and next to their member name when they post in the forums. There is a different badge for each research project and beta testing. To read more about badges, click here. Forums In addition to providing information about this project, we have created a forum for discussions about the Help Cure Muscular Dystrophy – Phase 2 project. To participate in this forum, please press the Forums button in the upper navigation bar or click here. Only forum authors with the title "Help Cure Muscular Dystrophy Scientist" are authorized to comment as representatives of the research organizations: Unversite Pierre et Marie Curie (Paris, France) and CNRS (Lyon, France). Project Participation The Help Cure Muscular Dystrophy – Phase 2 project is the fourteenth research project to be launched on World Community Grid and one of nine projects currently active. The other eight active research projects are: Influenza Antiviral Drug Search (launched May, 2009), Help Fight Childhood Cancer (launched March, 2009), The Clean Energy Project (launched December, 2008), Nutritious Rice for the World (launched May, 2008), Help Conquer Cancer (launched November, 2007), Discover Dengue Drugs – Together (launched August, 2007), Human Proteome Folding - Phase 2 (launched July, 2006) and FightAIDS@Home Phase 2 (launched November, 2005). For more detailed information and FAQs about each of these projects, please click on the Research button in the upper navigation bar or click here. We thank all of our members for their valuable contributions to the projects to date and hope you will continue to help us process those, as well as this latest project. Because there are nine research projects running on World Community Grid, your grid agent could receive work units from any of the projects depending on your Project profile. If you prefer, you may elect to focus your computer's time only on particular projects. To do so, press the My Grid button in the upper navigation bar and select My Projects or click here. Work is sent only to machines which meet minimum system requirements set for a particular project. To read more specifics on the system requirements for the Help Cure Muscular Dystrophy – Phase 2 project and the other projects, click here. Questions? If you have any questions, World Community Grid provides you with four methods of obtaining assistance: (1) Review the FAQs found in the HELP section of the website; (2) Review the forums to see if anyone has asked/answered the question that you have; (3) Ask the question in World Community Grid's Help Cure Muscular Dystrophy – Phase 2 project forum found here and a Community Advisor or a more experienced member will provide an answer; or (4) Send an email to the support desk from the Contact Us link found at the bottom of every page of the website (except in the forums). We thank you for contributing to the Help Cure Muscular Dystrophy – Phase 2 project.

大意：
帮助治愈肌营养不良症二期项目开工。

vmzy

Jun 26, 2009 8:44:07 PM
Possible outage to happen on DDDT (6/26/2009)

Greetings,

In about 36 hours we may run dry on new work for Discovering Dengue Drugs - Together. We are working with the researchers to get new work batch 1602 from them quickly but we may not be able to build them in time before the outage occurs.

This only affects members who have DDDT selected as their only project as other projects will still have work available during this time.

Thank you for your patience,
-Uplinger
大意：DDDT要断粮了，不过我们正在准备上传1602号新任务。

vmzy

Jul 7, 2009 6:48:34 PM
World Community Grid wins prestigious Coffey Award

We're pleased to let you know that World Community Grid was selected as winner of the 2009 Coffey International Award.

Here are the details of the award. You'll see that Prince Charles presented the award to the top IBM person in Europe.

http://www.bitc.org.uk/media_cen ... national_award.html

We thank you for your contribution to making World Community Grid a continued succes.
大意：
WCG获得Coffey 奖，感谢大家的支持与付出。

vmzy

官方本周例行维护时，发现主文件服务器硬盘文件系统故障，现在正在排险中。WCG随时可能断粮。
注：当前HCC癌症项目任务比较多，CEP清洁能源项目已断粮。

更新：
11：28 官方说文件系统已修复完毕，开始上传任务了。危机解除。

[ 本帖最后由 vmzy 于 2009-7-9 11:41 编辑 ]

vmzy

Jul 15, 2009 3:37:43 PM
Final Batches of DDD-T Phase 1 have been loaded.

Greetings everyone,

Discovering Dengue Drugs - Together Phase 1 is almost complete!!!! biggrin

I have loaded in the last new work from the researchers last night. I am estimating that new work for DDD-T will last for about 12 days. This means that after all of the new work has been sent out, members with DDD-T selected as their only project may start seeing "No new work available for the projects selected". It will take about 10-14 days after that last new work unit has been sent to actually return all of the results to the researchers. This is due to make up work units being sent out to additional hosts for calculations.

Thank you for contributing towards this project as of this posting over 11261 years of CPU time have been completed!

-Uplinger

(Note: these numbers are just estimates and may be off by a day or so).
大意：
DDD-T 项目1期即将结束，刚把最后一包任务上传了，请大家做好相应准备。

vmzy

Jul 22, 2009 2:24:59 PM
Congratulations! 300,000,000 Results returned to Accelerate Research!

We are extremely pleased to announce that World Community Grid volunteers have now returned more than 300 Million results. Results are what come out of each unit of work that you "crunch" on your computer and are sent to the researchers for analysis.

Our heartfelt thanks to the volunteer force -- the over 450,000 registered members who have downloaded World Community Grid on their computers. These computers have provided more than 258 thousand years of run time toward important research. We are extremely grateful for your contributions. Without you, this compute power would not be available for the very important research work we are helping to accelerate.
大意：
WCG返回结果总数突破3亿。

alexpon

Discovering Dengue Drugs – Together (Phase 1) Completion  
--------------------------------------------------------------------------------
World Community Grid is pleased to announce that as a result of the immense contribution of computing power from our members, Phase 1 of the Discovering Dengue Drugs – Together project finished on August 11, 2009.

The project launched on August 21, 2007 and ran for nearly 2 years. During that time over 159,000 members processed more than 25,500,000 results which required nearly 12,000 years of computing power from about 400,000 computers.

The project was interrupted for 17 weeks when Hurricane Ike made landfall in Galveston, Texas, USA, on September 17, 2008 and significantly damaged the research facility. Fortunately, none of the members of the research team and their families were injured and the facility was put back in working order. The project was re-started in late January, 2009.

A part of this project end, we also made some website updates. On the Research Pages and in the forums, the project is moved from Active Research to Completed Research.

Completing this project is a significant contribution to the research of Dengue Fever, Hepatitis C, West Nile, Yellow Fever and other diseases caused by the Flaviviridea family of viruses. This same research would have taken 205 years to complete on the computers that the researchers from UTMB had available to them in 2007.

Phase 1 was designed to serve as a comprehensive screening of approximately 3 million small "drug-like" molecules and identify several thousand molecules which attach to these virus enzymes in a manner that disables them. Molecules such as these may lead to drugs which can keep the disease from spreading in the body. The purpose of Phase 1 was to reduce the number of molecules being examined to only those that are the most promising candidates. These molecules will be further examined in Phase 2.

Phase 2 of the project will run each of the molecules identified in phase 1 through computationally demanding free energy calculations. The molecules that make it through this screening will be the candidates that show the most promising interactions with the virus enzymes and will be taken forward and further examined in the laboratory.

At this time, the researchers are busy performing post-processing on the results from Phase 1 and preparing for Phase 2. You may read about these plans and get the latest update from Dr. Stan Watowich in the following forum thread: http://www.worldcommunitygrid.or ... hread?thread=26616.

On behalf of the Discovering Dengue Drugs - Together research staff at the University of Texas Medical Branch in Galveston, Texas, USA, we wish to express our thanks to you for contributing your computer power to this project. With your contribution, this phase of the project was completed in a fraction of the time it would otherwise have taken.

While we wait for Phase 2 to start, we still need your help with eight (8) other ongoing projects! World Community Grid continues to run the FightAIDS@Home, Help Conquer Cancer, Help Cure Muscular Dystrophy - Phase 2, Help Fight Childhood Cancer, Human Proteome Folding - Phase 2, Influenza Antiviral Drug Search, Nutritious Rice for the World, and The Clean Energy Project. All of these important projects need your computer time.

IMPORTANT: If you have elected to participate only in the Discovering Dengue Drugs - Together project, you must take some action to prevent your World Community Grid agent from sitting idle on your computer until the next phase of the project launches. Please sign in to World Community Grid, and from the "My Grid" page, select the "My Projects" link (http://www.worldcommunitygrid.org/ms/viewMyProjects.do) from the menu on the left. From the "My Projects" page, select one or more of the other projects in which you choose to participate or check the box labeled “If there is no work available for my computer for the projects I have selected above, please send me work from another project” and then press “save”.

登格熱 藥物  計畫 第一階段完成  第二階段近期展開

zglloo

ye 今天看到邮件有提示 继续坚持！

vmzy

Oct 15, 2009 1:12:09 AM
The Clean Energy Project (Phase 1) Completion
World Community Grid is pleased to announce that as a result of the generous contribution of computing power from our members, Phase 1 of The Clean Energy Project finished on October 13, 2009.

The project launched on December 5, 2008 and ran for less than a year. During that time over 57,000 members processed almost 2 million results which required over 2,000 years of computing power from over 121,000 computers.

With the completion of this project, our members have significantly contributed to the research of discovering new materials that efficiently harvest solar radiation for the next generation of solar cells. This research information has helped determine which materials are most promising for developing affordable solar energy technology. This same research would have taken 22 years to complete on a regular scientific cluster.

Phase 1 was designed to perform molecular mechanics calculations: Some of the computers contributing to the Clean Energy Project are carrying out molecular mechanics calculations of molecular crystals, thin films and molecular and polymer blends to study the packing arrangements and for predicting charge and excitation energy transport properties of the candidate materials. These calculations will be carried out using the CHARMM molecular mechanics package developed by the Karplus group at Harvard University.

Phase 2 of the project will perform electronic structure calculations: To obtain the relevant optical and electronic transport properties, some of the computers connected to the Clean Energy Project will be computing calculations using wave function methods (such as Hartree-Fock or second-order perturbation theory) and density functional theory. These calculations will help researchers build a database of molecular properties that together with the results of the molecular mechanics calculations will help us identify potential candidate materials. The electronic structure calculations will be performed with the Q-Chem quantum chemistry code, developed by Q-Chem, Inc.

At this time, the researchers are busy performing post-processing on the results from Phase 1 and are preparing for Phase 2. You may read about these plans and get the latest update from The Clean Energy Project Scientists in this forum thread .

On behalf of The Clean Energy Project research staff at Harvard University, USA, we wish to express our sincere gratitude to you for contributing your computer power to this project. With your contribution, this phase of the project was completed in a fraction of the time it would otherwise have taken.

While we wait for Phase 2 to start, we still need your help with seven (7) other ongoing projects! World Community Grid continues to run the Help Cure Muscular Dystrophy - Phase 2, Influenza Antiviral Drug Search, Help Fight Childhood Cancer , Nutritious Rice for the World , Help Conquer Cancer , Human Proteome Folding - Phase 2 and FightAIDS@Home . All of these important projects need your computer time.
大意：
清洁能源1期结束

zglloo

Web Site updates for October 14, 2009  

--------------------------------------------------------------------------------
Today we are pleased to announce that we have released a new version of the World Community Grid website. The changes in this release of the website are as follows:

We have redesigned our home page and substantially altered the appearance of the entire website. This new look is designed to make the research projects the focus and encourage new people visiting our site to join and contribute to the research we are doing here.

We have also taken some steps to make it easier for our members to keep up to date on what is going on at World Community Grid. The new interface that we have released also allows members to easily browse news items and updates for each project and filter the news to only those items that they are interested in. An RSS feed is available for this news feature as well.

大致意思是
我们重新设计了我们的主页，大大改变了整个网站的外观。这个新面貌，是为了使研究项目突出重点和鼓励新的人来我们的网站加入，并有助于我们在这里继续研究。

[ 本帖最后由 zglloo 于 2009-10-28 15:10 编辑 ]

BiscuiT

End of the Infulenza Antiviral Drug Search Project


【Influenza Antiviral Drug Search】第一阶段已经完成

http://www.worldcommunitygrid.or ... thread_thread,27840

http://www.worldcommunitygrid.or ... thread?thread=27884